KMID : 1007520180270051519
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Food Science and Biotechnology 2018 Volume.27 No. 5 p.1519 ~ p.1524
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Release of N-nitrosamines and N-nitrosatable substances from baby bottle teats and rubber kitchen tools in Korea
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Park Se-Jong
Jeong Mi-Jin Park So-Ra Choi Jae-Chun Choi Hee-Ju Kim Mee-Kyung
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Abstract
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Ensuring the safety of baby bottle teats and kitchen tools made from rubber is critical. Therefore, the migration of N-nitrosamines and N-nitrosatable substances from 30 teats and 45 kitchen tools to artificial saliva was analyzed by liquid chromatography?tandem mass spectrometry. The method was validated by assessing the limits of detection (0.46?3.87 ¥ìg/kg), limits of quantification (1.38?11.73 ¥ìg/kg), and recoveries (86.3?108.6%) of seven compounds. Nitrosodimethylamine (NDMA), N-nitrosopiperidine, and N-nitrosomorpholine (NMOR) migrated from baby bottle teats at concentrations of not detected (ND) to 3.67 ¥ìg/kg. NDMA and NMOR concentrations ranged from ND to 1.72 ¥ìg/kg after migration from 45 rubber kitchen tools. N-nitrosatable substances ranged from ND to 42.16 ¥ìg/kg after migration from baby bottle teats but did not migrate from rubber kitchen tools. All tested products were considered safe for use, as N-nitrosamine and N-nitrosatable substance levels did not exceed the permitted management specifications.
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KEYWORD
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N-nitrosamines, N-nitrosatable substances, Baby bottle teat, Rubber kitchen tool, LC?MS/MS
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